产品货号：
Z18515
中文名称：
ING3抗体
英文名称：
Anti-ING3 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ING3 Antibody |
| 指标别名 | Eaf4;ING2;ING3;Inhibitor of growth protein 3;p47ING3 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB |
| 基因名称 | ING3 |
| 抗体来源 | Goat |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 285-310 of Human ING3 protein (Inhibitor of growth family,member 3). |
| 计算分子量 | 47kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This is an affinity-purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.Reactivity occurs against human p47 ING3 protein.This sequence only shows homology to isoform 1 for ING3.The sequence is not present in isoforms 2 and 3.However,100% homology is on record for this protein from human,dog,rat,chimpanzee and orangutan.Cross-reactivity with p47 ING3 protein from mouse and chicken sources is also expected based on high homology (one amino acid change in sequence) by BLAST.Reactivity with p47 ING3 proteins from other sources is not known. |
| 浓度 | 1.10mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | p47 ING3 is a tumor suppressor protein similar to ING1 that can interact with TP53,inhibit cell growth,and induce apoptosis.This protein contains a PHD-finger,which is a common motif in proteins involved in chromatin remodeling.This gene can activate p53 trans-activated promoters,including promoters of p21/waf1 and bax.Over-expression of this gene has been shown to inhibit cell growth and induce apoptosis.Allelic loss and reduced expression of this gene were detected in head and neck cancers.Multiple alternatively spliced transcript variants have been observed.The accession number listed below is for variant (1) that encodes the longest isoform. |
| Uniprot ID | Q9NXR8 |
| 基因名全称 | Inhibitor of growth protein 3 |
| 推荐稀释比 | ELISA:1:10,000 - 1:40,000 WB:1:200 - 1:2,000 |
相关搜索：ING3抗体，ING3多抗，Anti-ING3 Antibody